5HolisticSecrets

The 5 Holistic Secrets

Learn the Five Pillars of Health and Well-Being and Hold The Keys to Optimal Health

These overlooked practices are the keys to reversing chronic disease, overcoming chronic pain, effortlessly losing weight and creating lasting radiant health and longevity.

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"Physical, Emotional and Spiritual Health"

Live Well is a premier Holistic Wellness center providing comprehensive wellness services and live source, excipient free nutraceuticals from Premier Research Labs designed to nourish and/or detoxify your cells, organs and glands. Our mission is to empower you to achieve radiant physical, emotional and spiritual health. Learn More About Us

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Holistic Strategies for Weight Management 

Written by Lauren Hayden. Posted in Educational Series, Weight Management

Lasting Lifestyle Solutions For a Healthy Life 

Join Lauren Hayden and learn the truth about achieving and maintaining healthy weight.  You will learn the 5 essential lifestyle factors;  foods to eat and how to prepare them;  what foods to eliminate; and why fad diets and most weight loss products can be dangerous to your health.  

Tuesday, October 11, 2016
5:30 – 6:30 pm
Refreshments will be served
Raffle for free 1 hour consultation!  ($150.00 value)

Location
Millennium Medi Spa
4407 Willard Avenue
Chevy Chase, MD 20815
703-929-6855
RSVP to:  Lauren@livewellva.net

“Empowering you to achieve radiant health and well-being”

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Prevention and Treatment of Osteoarthritis

Written by Lauren Hayden. Posted in Athletic Performance, Mineral Support, Nutritional Support

Phytonutrient and Mineral Therapies for the Prevention and Treatment of Osteoarthritis

Osteoarthritis (OA) is a progressive degenerative disease of the diarthrodial joints especially those that are weight bearing (Danning, 2013), including the knees, hips, shoulders and spine, but can occur at any joint.  Figure 1 contains the diarthrodial joints.  OA is characterized by the degeneration of articular cartilage and formation of subchondral bone and new bone at the joint margins (Danning, 2013). Increasing age correlates with the progressive nature of the disease (but does not cause the disease) finding the highest incidence in populations over 70 years.  Postmenopausal woman are greatly affected in the knee and hand joints. 

The etiology of osteoarthritis results from mechanical and/or biochemical factors.   Mechanical causes include misalignment of the joint, wear and tear of joints due to obesity, previous joint trauma/injury including surgeries and congenital disorders.  Biochemical causes include dehydration, mineral and nutritional deficiencies, hormonal imbalances and genetic predisposition (Danning, 2013).  We will briefly describe the pathophysiology of OA and present complementary and alternative medical (CAM) nutritional therapies for the prevention and treatment of osteoarthritis induced by biochemical causes. 

Biochemical pathophysiologic factors leading to degeneration of articular cartilage result from alterations in numerous biological systems including pH, bone remodeling and protein activities that influence the health of synovial fluids and articular cartilage.    The synovial fluids bathe the joint capsule reducing friction between cartilages and protecting joint tissues.  Movement is essential for healthy joint function as fluid is forced from the cartilages when a join is compressed from pressure and movement (Marieb, 2013).  The presence of calcium phosphate crystals in joint fluid has been shown by some studies to suggest hydroxyapatite formation (Yavorskyy & Santana & McCarthy 2008).  Chronic synovial inflammation induced by calcium crystal deposits could result in chronic polyarthritis (Yavorskyy et al. 2008). Calcification of hydroxyapatite and calcium crystals accentuates the degeneration process by cutting off nutrient supply of glucose and oxygen and interfering with the removal of metabolic waste (Paesold & Nerlich & Boos, 2007). 

The pH of synovial fluids is essential for healthy joint function.  Hyaluronic acid which lubricates surfaces between synovium and cartilage is more stable in conditions of a pH of 7.2-7.4 (Yavorskyy et al. 2008).  Measurements in spinal vertebrae demonstrate low oxygen concentration and elevation in lactic acid which lowers the pH inside the disc.  Low oxygen concentrations and acidic pH affect proteoglycan synthesis rates of vertebral disc cells which may lead to reduction of proteoglycan content and disc degeneration (Paesold, et al. 2007).  CAM nutritional strategies are to upregulate the microenvironment of the joint capsule by prevention and treatment of bone loss, hydroxyapatite formation and to optimize pH of body fluids

Water Hydration of the articular cartilage is essential for joint lubrication and cushioning of weight bearing joints to protect from wear and tear.  Articular cartilage is composed of proteoglycan, collagen fibril and water, the most abundant component.  Water allows the swelling of the collagen–PG matrix providing stability and cushioning.  Hydration is essential for cartilage to maintain normal function, structural integrity and prevent rupture. Dehydrated cartilage is more easily ruptured than hydrated cartilage (Wang & Yang & Niu et al. 2013).  Sixty percent of bodyweight in water is recommended, with an additional 24 oz per hour of exercise.

Glucosamine Sulfate Glucosamine Sulfate (GS), composed of glucose and an amine, promotes targeted support for joints and connective tissue.  Production of GS abates with age resulting in degeneration of cartilage (Murray, 2013). GS is a component of glycoproteins, proteoglycans and glycosaminoglycan’s (Dalirfarouei & Karimi & Jamialahmadi, 2016) and promotes the incorporation of sulfur into cartilage (Murray, 2013). GS also has antioxidant and anti-inflammatory properties (Dalirfarouei et al. 2016).  GS and a mud bath treatment were shown to improve pain, function and quality of life in patients with osteoarthritis (Peluso & Caso & Costa et al. 2016).

Vitamin K  Fat soluble vitamin K is a cofactor for calcium binding proteins and an inhibitor of bone demineralization and calcium crystal growth (Shea & Kritchevsky & Hsu et al. 2015).   Cartilage and meniscal calcification are implicated in the pathogenesis of OA and Vitamin K cofactor for matrix gla proteins inhibits ectopic mineralization by binding calcium crystals and inhibiting calcium crystal growth (Shea et al. 2015).   Vitamin K2 helps prevent bone resorption through stimulation of the gene expression of osteoblasts and the upregulation of osteocalcin activity (Marshall, 2016). 

Aquamin Red Algae (lithothamnion sp) Mineralized Red Algae is rich in calcium, magnesium and 72 other trace minerals (Marshall, 2016).  It reduces the symptoms of osteoarthritis and aids in the mineralization and maturation of osteoblasts (Marshall, 2016).  Red Algae also regulate the pro-inflammatory activity of NFkB (Marshall, 2016).

Vitamin D Insufficient vitamin D levels are implicated in an increased risk of OA.  Bassiouni & Aly & Zaky et al. (2016) found the mean values of Vitamin D were statistically lower in knee OA patients.  Significant deterioration of the medial menisci was also observed in vitamin D deficient OA patients (Bassiouni et al 2016).  Low D levels predict loss of cartilage as shown by reduced joint space and osteophyte growth (Murray, 2013). Live source vitamin D3 from sheep’s lanolin is an ideal source from PRLabs.  Recommended dose is at least 2,000 IU daily.  Individuals over the age of 40 and those with gallbladder malfunction can take 12,000 IU with food grade organic limonene oil (Marshall, 2015)

Calcium Adequate levels of calcium are essential for healthy bones, electrolyte balance and the prevention of bone loss. Low calcium intake will increase bone resorption, decrease bone mineralization (Carmeliet et al. 2015) and can lead to formation of  hydroxyapatite crystals which are often found in synovial fluids of OA  patients.( Yavorskyy et al. 2008).

 Natural occurring calcium from greens and marine coral are the ideal options.  Oat Grass, Avena sativa contains a rich array of essential minerals including calcium, potassium, phosphorus, magnesium, chromium, iron and selenium (Marshall, 2015).  Studies show Oat Grass stimulates cell growth including osteoblasts (Marshall, 2015).  Sango marine coral from Okinawa is 90 % ionized, highly absorbed and an ideal 2:1 ratio of calcium and magnesium. (Marshall, 2015).

 

References

Bassiouni, H., Aly, H., Zaky, K., Abaza, N., & Bardin, T. (2016). Probing tThe relation between Vitamin D deficiency and progression of medial femoro -tibial osteoarthitis of the knee. Current Rheumatology Reviews. Abstract retrieved from PMID:

Carmeliet, G., Dermauw, V., & Bouillon, R. (2015). Vitamin D signaling in calcium and bone homeostasis: A delicate balance [Abstract]. Best Practice and Research: Clinical Endocrinology Metabolism, 621-31. doi:10.1016/j.beem.2015.06.001

Dalirfardouei, R., Karimi, G., & Jamialahmadi, K. (2016). Molecular mechanisms and biomedical applications of glucosamine as a potential multifunctional therapeutic agent. [Abstract]. Life Sciences, 179-85. doi:10.1016/j.lfs.2016.03.028.

Danning, C. (2013). Alterations in musculoskeletal function: rheumatic disorders. In L. E. Copstead & J. Banasik (Eds.), Pathophysiology (5th, pp. 1039-1042). St. Louis, Missouri: Elsevier Saunders.

Marieb, E., & Hoehn, K. (2013). Joints. In S. Beuparlant (Ed.), Human Anatomy & Physiology (9th, pp. 249-270). Glenview, IL: Pearson Education, Inc.

Marshall, B. (2015, June 9). No Bones About it, Nutrition is Vital for Bone Health [Webinar]. Retrieved from www.PRLabs.com

Murray, M. (2013). Osteoarthritis. In J. Pizzorno & M. Murray (Eds.), Textbook of Natural Medicine (4th, pp. 1651-1661). St. Louis, Missouri: Elsevier, Churchill Livingstone.

Paesold, G., Nerlich, A. G., & Boos, N. (2007). Biological treatment strategies for disc degeneration: potentials and shortcomings. European Spine Journal, 447-468. doi:10.1007/s00586-006-0220-y

Peluso, R., Caso, F., Costa, L., Sorbo, D., Carraturo, N., Di Minno, M. N., . . . Scarpa, R. (2016). Mud-bath therapy and oral glucosamine sulfate in patients with knee osteoarthritis: a randomized, controlled, crossover study. Clinical and Experimental Rheumatology. Abstract retrieved from PMID: 27050908

Shea, M., Kritchevsky, S., Hsu, F. C., Nevitt, M., Booth, S., Kwoh, C. K., . . . Loeser, R. F. (2015). The association between vitamin K status and knee osteoarthritis features in older adults: The Health, Aging and Body Composition Study [Abstract]. Osteoarthritis Cartilage, 370-378. doi:10.1016/j.joca.2014.12.008

Wang, Q., Yang, Y. Y., Niu, H. J., Zhang, W. J., Feng, Q. J., & Chen, W. F. (2013). An ultrasound study of altered hydration behaviour of proteoglycan-degraded articular cartilage. BMC Musculoskeletal Disorders. doi:10.1186/1471-2474-14-289

Yavorskyy, A., Hernandez-Santana, A., McCarthy, G., & McMahon, G. (2008). Detection of calcium phosphate crystals in the joint fluid of patients with osteoarthritis – analytical approaches and challenges. Analyst, 302-318. doi:10.1039/b716791a

 

 

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Liver Gallbladder Spring Detox with Qigong

Written by Lauren Hayden. Posted in Detoxification, Detoxification and Cleansing Support, Digestive Support, Educational Series, Energy Support

Qigong and Liver Gallbladder Detox

 

The Ultimate Detox for Rejuvenation and Disease Prevention

 

Join Pauline and Lauren for a fabulous day of energy healing and rejuvenation.  We will begin with an introduction to Qigong barefoot on the grass so dress warmly! Pauline Reid, Qigong instructor will share this powerful Chinese energy healing art.  Qigong, has been practiced for thousands of years in the East to create and maintain health through the balance of  mind, body and spirit. This introductory class will enlighten you to this ancient art and the numerous ways it will benefit your health.  Pauline will share her wisdom as we explore some simple movements and breathing exercises that easily integrate into our daily lives. Movements to support the Liver and Gall Bladder will be the focus in this session, to ground, energize and prepare us for a busy spring season.  

Join Lauren Hayden, energy, nutrition and detoxification expert and learn  the metabolic functions of the liver and gallbladder highlighting their essential role in  weight management, digestion of macro and micro nutrients and disease prevention.  You will learn the connection of the liver gallbladder to weight management, hormone and brain health.  Lauren will take you through the three easy steps to a healthy liver gallbladder that can be done in the comfort of your own home.   Mark your calendar and join us for this fabulous day of rejuvenation as we awaken, ground and provide you with the tools you need for a healthier mind, body and soul.

Sunday, April 10, 2016
1:30 – 4:30 pm
Qigong and Seminar Cost $60.00
or separate
Qigong Session $25.00
Liver Gallbladder Detox $ 40.00

 Live Well LLC
5721 Windsor Gate Lane
Fairfax, VA 22030
703-929-6855

RSVP to:  Lauren@livewellva.net



 

Qigong Energy Session           1:30 – 2:45
Refreshments                           2:45 – 3:00    
Liver/Gallbladder                      3:00 – 3:45
Workshop                                  3:45 – 4:30

Liver Gallbladder Seminar  

A. Function of the Liver and Gallbladder
B. Why a Liver Gallbladder flush is essential in our toxic world
C. Benefits of a Liver Gallbladder Detox

  • Cleanse and strengthen the liver
  • Cleanse and strengthen the gallbladder
  • Cleanse the blood
  • Strengthens the immune system
  • Improve fatty acid metabolism
  • Improve hormone function
  • Improve cholesterol metabolism
  • Improve elimination and relief from constipation
  • Weight loss and reduction in body fat
  • Disease preventive strategy
  • Radiant hair, skin and nails
  • Improve your sleep
  • Improve mood and irritability
  • Remove small gallstones from the gallbladder
  • Minimize risk of osteoporosis
  • Change of lifestyle, improved health, well-being and committment
  • Workshop in the kitchen 3:45- 4:30

    Simple instructions, simple solutions

  • Coffee enema procedure
    Gallbladder flush procedure

“Empowering you to achieve radiant health and well-being”

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Introduction to Qigong

Written by Lauren Hayden. Posted in Uncategorized

Introduction to Qigong 
Barefoot on the Lawn in Nature to Rejuvenate  Mind, Body and Soul

 

Join Pauline Reid, Qigong instructor for a powerful Chinese energy healing session barefoot on the lawn in nature!  Qigong, has been practiced for thousands of years in the East to create and maintain health through the balance of  mind, body and spirit. This introductory class will enlighten you to this ancient art and the numerous ways it will benefit your health.  Pauline will share her wisdom as we explore some simple movements and breathing exercises that easily integrate into our daily lives. Spring is the season for Liver, a time of awakening, growth, and rising energy.  Movements to support the Liver and Gall Bladder will be the focus in this session, to ground, energize and prepare us for a busy spring season.  Handouts will be available.

Sunday, April 10, 2016
1:30-2:45 pm
Qigong Session Cost $ 25.00
Full Seminar Cost $ 60.00

Location
Live Well LLC
5721 Windsor Gate Lane
Fairfax, VA 22030
703-929-6855
RSVP to:  Lauren@livewellva.net

Liver Gallbladder Detox Seminar and Workshop will follow click here for details

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Cardio Protective Nutrition for a Healthy Heart

Written by Lauren Hayden. Posted in Athletic Performance, Detoxification, Energy Support, Mineral Support

“Prevent cardiovascular disease,  understand the causes,  empower yourself to take action”

Atherosclerosis is the leading cause of cardiovascular disease and mortality in the industrialized world.  Current theories on the etiology of CVD formation include the endotoxin theory of damage to the tunica, the inflammation and oxidation of cholesterol theory and the hydroxyapatite theory of calcium formation.   This literature review explores six leading phytonutrients and minerals, Bear garlic (Allium ursinum), Garlic (Allium Sativum), Turmeric (Curcuma longa), Delta Tocotrienol, and Vitamin D3 and Coral Calcium, shown effective against the causes of atherosclerosis.  Along with a healthy diet, exercise and stress management we found that phytonutrients from plants and minerals are effective in the prevention and treatment of atherosclerosis.

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Disease Prevention Strategies for 2016

Written by Lauren Hayden. Posted in Detoxification, Detoxification and Cleansing Support, Energy Support, Mineral Support, Nutritional Support

 

  • As we contemplate our wellness resolutions this New Year, consider integrating a detoxification, nutritional supplementation and stress management component to your wellness program.   Mark your calendar and join us for an open house to learn simple strategies to make 2016 your year to learn the latest  disease prevention techniques and the importance of  detoxification.

    Sunday, February 28, 2016
    3-5 pm
    Seminar Cost $40.00
    (applied toward consultation)

    Live Well LLC
    5721 Windsor Gate Lane
    Fairfax, VA 22030
    703-929-6855

    Detoxify

    Acute or chronic toxicity from environmental chemicals, infectious agents (bacteria, viruses and parasites) and electromagnetic radiation stress or injure our cell (Banasik, 2013). Toxicity can cause disease and is the number one challenge facing our health today (Sears, 2013).  Chronic toxicity can alter cellular function and the microenvironment of the cell (Casey, Amedei, Aguilano et al 2015)   leading to diseases  including, cardiovascular, endocrine disorders (thyroid, hormonal imbalances) neurodegenerative disorders (Alzheimer’s, Multiple Sclerosis, Parkinson’s) and many cancers including breast, prostate (Sears, 2013) and blood cancers including leukemia.

    Internal detoxification is the elimination of internal stressors including bacteria, viruses, parasites, and environmental toxins from pesticides and heavy metals which suppress the immune system and interfere with cellular communication and or function (Copstead & Banasik, 2013). Many phytonutrients and minerals have been targeted as inhibitory agents capable of influencing tumorigenesis and stimulating apoptosis of cancer cells cell (Casey, Amedei, Aguilano et al 2015).  Many FDA approved, herbal botanicals (phytonutrients) support internal detoxification including:

    • Allicidin effectively eliminates candida and other bacteria
    • Medi-clay FX and Gamma Detox  promote intracellular and extracellular detoxification
    • Cardio ND is a blood cleanser shown to safely and effectively support healthy blood pressure and cardiovascular health
    • Immuno ND detoxifies the lymph improving immune function
    • Oregano Oil, Olive Leaf and Premier HCL detoxify viruses supporting immune function of white blood cells

    Nutrify

    A healthy diet is essential, difficult to maintain and typically not enough to prevent and reverse disease.  Nutritional deficiencies and infection may provide stimulus for disease and cancer cell proliferation (Banasik, 2013). Provide your cells with the phytonutrient (plant based nutrients) through supplementation and dietary support to keep your cells and organs working at optimal function.

    Focus your programs on:

    • Correcting nutritional deficiencies
    • Supporting the immune system
    • Balancing the pH of the bodily fluids through dietary and mineral support
    • Improving the digestion and absorption of micro and macronutrients

    De-Stress

    Exercise has been clinically shown to be essential to our health and well-being due to increased cellular metabolism and stress reduction. Benefits of exercise include:

    • Increases oxygen and cellular detoxification
    • Increased ventilation and circulation
    • Stress relief through release of catecholamines and stress hormones  (Seaward, 2015)
    • Physical stimulation prevents homeostatic dysfunction
    • Increases physical fitness and quality of life
    • Reduces fatigue
    • Improve energy and stamina
    • Promotes weight loss through activation of fat and carbohydrate metabolism.

    “Empowering you to achieve radiant health and well-being”

     

 

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Savings Incentive Plan – Save up to 10%

Written by Lauren Hayden. Posted in All, Customer Incentives

Savings Incentive Plan – Take Advantage and Save up to 10%

1. Order Incentive Program

Important Note:  Orders must be placed before the end of the second week of each month.

This program is designed to reward you for staying consistent with your health and the health of your family. It also benefits Live Well by cutting down on our cost of goods sold and stream-lining inventory and ordering so we can pass the savings on to you!

The Order Incentive Program applies to minimum orders over $50.00 per month, and includes all consultations services!

You will receive a discount coupon at checkout based on your product and service volume of about 10 percent per order.

Here are the codes for your convenience:

Coupon           Order Amount         Coupon Value

Red                    $ 50.00                         $ 5.00    

Orange              $100.00                        $10.00

Yellow               $150.00                        $15.00

Green                $200.00                        $20.00

Blue                   $250.00                        $25.00

Indigo                $300.00                        $30.00 

Orders must be made online to participate. Live well will be happy to place orders for you, but discounts will not apply. 

Please feel free to call 703-929-6855 or email lauren@livewellva.net if you need more information.

To your health and wellness,

Lauren

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Anti-Inflammatory Effects of Turmeric and Ginger

Written by Lauren Hayden. Posted in All, Detoxification, Nutritional Support, Uncategorized

Anti-Inflammatory Effects of Turmeric and Ginger

The inflammatory response is the body’s natural response to tissue injury of any kind.  It results in increased vascular permeability by the release of vasoactive and chemotactic factors to begin the repair and healing process, the emigration of leukocytes to clear debris and phagocytosis of collagen and extracellular matrix degradation.  Oxidation is a necessary, yet a destructive element of the inflammatory process and can lead to oxidative stress resulting in chronic inflammation as the body struggles to repair itself.  Many natural herbs have been clinically shown to be effective antioxidants and anti-inflammatory agents.  We will discuss the inflammatory process and provide current research on the anti-inflammatory effects of Turmeric (Curcumin longa) and Ginger (Zingiber officinale).

Inflammation and Oxidative Stress

Inflammation occurs when cells are injured by either endogenous (internal) or exogenous (external) injuries (Banasik, 2013).  Endogenous injuries from surgeries and physical trauma damage tissue and interfere with cell signaling communication and cellular metabolism.  Exogenous sources from infections including pathogens (viruses, bacteria, yeast, mold, fungi and parasites) or foreign substances from environmental toxins also result in inflammation. Inflammation stimulates the body’s immune system which is designed to defend and eliminate these stressors by neutralizing and destroying harmful agents, limiting their proliferation to neighboring tissues and repairing damaged tissue (Banasik, 2013). 

Oxidizing agents are destructive byproducts of the inflammatory response because they attack cell membranes and can cause permeability releasing nitric oxide which reacts with oxygen to attack microbial molecules (Banasik, 2013).  Oxidative stress is defines as a disturbance in the balance between the production of reactive oxygen species (free radical and reactive metabolites) and the antioxidant defenses of the system to detoxify the reactive intermediates and repair the resulting damage (Wikepedia, 2015).  Oxidative stress can lead to chronic inflammation, disruptions in normal mechanisms of cellular signaling and DNA damage (Wikepedia, 2015) resulting in many diseases including pulmonary, neurological, diabetes, cardiovascular, and cancers (He, Yue, Zheng et al 2015) and many others.

Ginger (Zingiber officinale)

Ginger (Zingiber officinale) (root) has been used for thousands of years in China for medicinal purposes (Murray, 2013).  Its therapeutic actions include anti-emetic, gastrointestinal support, choloagogue, spasmolytic, anti-inflammatory, antibiotic, antioxidant, and anti-inflammatory (Murray, 2013).  We will discuss current research on the anti-oxidant and anti-inflammatory and anti-allergenic effects.  The active constituents that appear to demonstrate the antioxidant and anti-inflammatory activities are the phenolic compounds gingerol, shogaol, paradol, zingerone, zerumbone (Tahir, Sani, Murad et al 2015).  The anti-inflammatory effects of ginger are due to the inhibitory effect to reduce prostaglandin synthesis, leukotriene biosynthesis (Al-Nahain, Jahan and Rahmatullah 2014) thromboxanes and its other antioxidant activities (Murray, 2013).

Gingerols are phenolic substances found in the rhizome shown to have anti-inflammatory, anti-oxidant and anticancer properties (Wang, Zhang, and Yang et al 2014).  Inappropriate T lymphocyte function is implicated in the inflammatory process.  Gingerol extracts were shown to inhibit DNA synthesis by T lymphocytes and interferon-y synthesis (Bernard, Furlong and Power et al. (2015).   Gingerol (8) and gingerol (10) impaired IL-2 induced proliferation of CLL-2 cells through the inhibition of IL-2 receptor signaling. The anticancer activities of 6-Gingerol are via a variety of biological pathways involved in apoptosis, cell cycle regulation, cytotoxic activity and inhibition of angiogenesis (Wang et al 2014) the growth of new blood vessels. 

Zingerone from ginger is an anti-inflammatory agent shown to suppress acute systemic lipopolysaccharide (LPS) inflammation via nuclear factor (NF-kB) and proinflammatory cytokines in mice (Hsiang, Cheng, Lo, et al. 2015).  Zerumbone a sesquiterpene from wild ginger rhizome has been shown to contain ant carcinogenic, anti-inflammatory, antioxidant and antiallergenic properties (Shieh, Huang, Wang et al. 2015).  The antiallergenic properties are due to reducing allergen specific immunoglobulin E (lgE) and increasing lgG2a antibodies, preventing eosinophilic pulmonary infiltration and ameliorating mucus hypersecretion suggesting the anti-allergic effects result from modulation of Th1/Th2 cytokines (Shieh et al 2015).

Zingiber officinale and Gelam honey was shown to be have anti-inflammatory and anti-tumor effects against colorectal cancer by stimulation of apoptosis (upregulation of caspase 9 and lkB genes) and downregulation of the KRAS,ERK, AKT, Bclxl and NFkB (p65) genes (Tahir, Sani, Murad et al. 2015).   It has also been shown to ameliorate Rheumatoid arthritis by stopping RA-induced bone destruction (Al-Nahain, Jahan, and Rahmatullah 2014).

Curcumin

Curcumin longa (Turmeric) (root) has been used for 4,000 years as an herbal remedy in medicine.  It contains therapeutic action as an anti-arthritic, anti-asthmatic, antibacterial, anticarcinogenic, antifungal, antihyperlipidemic, anti-inflammatory, antioxidant, antiulcer, antiviral, cholagogue, expectorant, hepatic and hypoglycemic (Peterson, 2015).  We will discuss the anti-inflammatory and antioxidant effects in cardiovascular disease and rheumatoid arthritis. 

Curcumin has been shown to display anti-inflammatory activity and alleviate oxidative stress in chronic diseases through the Nrf2-keap1 pathway and through its natural chemical structure as a free radical scavenger (He et al., 2015).  Curcumin suppresses pro-inflammatory pathways and blocks the product of TNF by binding to TNF directly remediating TNF cell signaling in various cells (He et al., 2015).   As an antioxidant, curcumin is known to bind amyloids, stabilizing protein homeostasis networks (He et al., 2015).

Cardiovascular diseases have been shown to develop from oxidative stress, inflammation and activation of proinflammatory cytokines (He et al., 2015).  Curcumin was shown to protect against inflammation, cardiac hypertrophy and fibrosis by inhibiting p200-HAT activity and other signaling pathways (He et al., 2015).  Curcumin suppressed lipopolysaccharide (LPS) induced inflammation in vascular smooth muscle cells of rats by inhibition of TLR4-MAPK/NF-kB pathways (He et al., 2015).  Parodi et al. found mice treated with curcumin exhibited decreases in aortic tissue activator protein – and NF-kB DHA binding lowering concentrations of IL1B, IL-6, MCP-1 and MMP-9 (He et al. 2015).  Curcumin was shown to stimulate apoptosis of H9c2 cells by upregulating reverse oxygen species (ROS) and triggering the activation of JNK’s (He et al., 2015).

Rheumatoid arthritis (RA) is an autoimmune condition resulting in inflammation of the synovial joints.  ROS mediates many transcription factors that regulate gene expression, growth factors, chemokines and inflammatory cytokines suspected to play a role in RA.  Curcumin has raised a great deal of interest as a therapy for RA and clinical trials are under way.  Curcumin activated caspase-3 and -9, up regulated Bax, down-regulated Bcl-2 and Bcl-xL, degraded poly (ADP-ribose) polymerase in RA patients (He et al. 2015).  Curcumin showed anti-inflammatory response in synovial fibroblasts by suppression of COX-2 and inhibition of prostaglandin E2 synthesis (He et al. 2015). Lee et al also found in vitro that curcumin abolished the p65 NF-kB nuclear translocation and binding activity of NF-kB DNA  by inhibition of COX-2 and MMP-9 and reduction of IkBa phosphorylation in IL-1B and TNF –a-articular chondrocytes (He et al., 2015).

References

Al-Nahain, A., Jahan, R., & Rahmatullah, M. (2014). Zingiber officinale: A potential Plant against Rheumatoid Arthritis. [Abstract]. Arthritis. doi:10.1155/2014/159089

Banasik, J. (2013). Inflammation and immunity. In Pathophysiology (5th, pp. 157-193). St. Louis, Missouri: Elsevier Saunders.

Bernard, M., Furlong, S. J., Power Coombs, M. R., & Hoskin, D. W. (2015). Differential Inhibition of T Lymphocyte Proliferation and Cytokine Synthesis by [6]-Gingerol, [8]-Gingerol, and [10]-Gingerol. [Abstract]. Phytotherapy Research. doi:10.1002/ptr.5414

He, Y., Yue, Y., Zheng, X., Zhang, K., Chen, S., & Du, Z. (2015). Curcumin, inflammation, and chronic diseases: how are they linked? Molecules, 9183-213. doi:10.3390/molecules20059183

Hsiang, C. Y., Cheng, H. M., Lo, H. Y., Li, C. C., Chou, P. C., Lee, Y. C., & Ho, T. Y. (2015). Ginger and Zingerone ameliorate lipopolysaccharide-induced acute systemic inflammation in Mice, assessed by nuclear factor-?B bioluminescent imaging. [Abstract]. Journal of Agricultural and Food Chemistry, 63, 6051-8. doi:10.1021/acs.jafc.5b01801

Murray, M. T. (2013). Zingiber officinale (Ginger). In Tectbook of Natural Medicine (4th ed., pp. 1147-1153). St. Louis, Missouri: Elsevier, Churchill Livingstone.

Oxidative stress. (2015, October 31). In Wikipedia. Retrieved November 3, 2015, from Wikepedia Foundation Inc website: https://en.wikipedia.org/wiki/Oxidative_stress

Peterson, D. (2015). Essential oil of Turmeric. In http//www.achs.edu. Retrieved November 4, 2015, from American College of Healthcare Sciences website: http://myachsclass.org/re/DotNextLaunch.asp?courseid=11632021&userid

Shieh, Y. H., Huang, H. M., Wang, C. C., Lee, C. C., Fan, C. K., & Lee, Y. L. (2015). Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice. [Abstract]. International Immunopharmacology, 383-91. doi:10.1016/j.intimp.2014.12.027

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Simple, all natural, holistic way to prevent colds and flu!

Written by Lauren Hayden. Posted in All, Nutritional Support

Simple, all natural, holistic way to prevent colds and flu!

Great products to have on hand this time of year are Colostrum, AloeMannan-FX and or Oregano Oil to prevent colds and flu. 

To prevent cold or flu place one drop of Oregano Oil in water and drink before entering a public place. You can also put it in your water bottle.  It is really powerful and will pack a punch so do not put directly in the mouth.  Add one drop Limonene  Oil to cut it down.  It coats and kills anything coming into the buccal or nasal cavities coating the epithelium from top to bottom.  Great to have around the holiday season or traveling to the airport.  Do not give this to the kids, way too intense.

As soon as you feel a cold coming on immediately take one Colostum and 1 Aloe-Mannan-FX and let dissolve under the tongue 3 times daily.  This will stop the progression or ease the symptoms.  You can give this to your children in there morning or before school during cold season.

Feel free to call Lauren 703-929-6855 or email lauren@livewellva.net to discuss this and other winter wellness tips.

To your health and wellness!

 

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Slaying Dragons for Emotional Healing

Written by Lauren Hayden. Posted in All, Consultations, Educational Series

Emotional health is an essential component of the 21st century “Well-Being Paradigm” defined as physical, emotional, mental and spiritual balance. Positive affirmations and visualization techniques such as “Now I can be healthy,” “Now I can be loved,” or “Now I can be happy,” are essential for the healing process and moving toward higher levels of consciousness where the mind, body and soul are working in synchronicity to maintain homeostasis and enlightenment.

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Oral Contraceptives: A Risk Factor to Gallbladder Disorders

Written by Lauren Hayden. Posted in All, Detoxification, Digestive Support, Educational Series, Endocrine Support, Nutritional Support

Gallbladder disease affects an estimated 20 million Americans and is now the leading surgical procedure in the United States (Hoffman, 2014). Research as far back as 1975 reported on the necessity of administering Vitamin B6 to prevent excretion of tryptophan metabolites resulting from use of oral contraceptives in woman. More than 99 percent of women age 15-44 have used some form of contraceptive (Guttmacher, 2014) and oral contraceptives account for an estimated 17 percent, about 10 million American woman. Recent studies now link oral contraceptives as the leading risk factor in gallbladder disease in woman who have ever used oral contraceptives. Nutritional scientists identify vitamin B6 deficiencies as the principle cause of gallbladder disorders associated with oral contraceptive use. Supplementation with live source B6 is essential for the prevention of gallbladder disorders and disease in woman taking oral contraceptives.

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